Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842730 | 0.89 | TLR7 (0.42) | EGFRACP1ALDH1A1HPGDMAPT | |
| SCHEMBL7835249 | 0.83 | EGFR (0.45) | EGFRMAPTKMT2AMEN1MAPK1 | |
| SCHEMBL8870696 | 0.79 | EGFR (0.47) | EGFRACP1ALDH1A1HPGDMAPT | |
| SCHEMBL7832227 | 0.79 | EGFR (0.43) | EGFRACP1ALDH1A1HPGDMAPT | |
| SCHEMBL7835397 | 0.79 | EGFR (0.43) | EGFRACP1ALDH1A1HPGDMAPT | |
| SCHEMBL7824280 | 0.78 | POLB (0.38) | EGFRALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL7823369 | 0.73 | EGFR (0.44) | EGFRMAPTKMT2AMEN1MAPK1 | |
| SCHEMBL28560298 | 0.70 | ALDH1A1 (0.45) | EGFRALDH1A1HPGDMAPTLMNA | |
| SCHEMBL8114585 | 0.70 | ATM (0.47) | EGFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4726732 | 0.69 | MAPT (0.45) | ACP1ALDH1A1HPGDMAPTTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5395937-A | Process for preparing quinoline amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | disclosed |