Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835993 | 0.89 | EGFR (0.44) | TLR7EGFRACP1ALDH1A1HPGD | |
| SCHEMBL7823369 | 0.85 | EGFR (0.44) | EGFRMAPTKMT2AMEN1KDM4E | |
| SCHEMBL8114585 | 0.83 | ATM (0.47) | EGFRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8128780 | 0.78 | MAPT (0.33) | MAPTKMT2AMEN1MAPK1TDP1 | |
| SCHEMBL842831 | 0.78 | BCHE (0.44) | KMT2AMEN1RAB9AGAA | |
| SCHEMBL7824056 | 0.78 | CYP3A4 (0.36) | EGFRHPGDMAPTLMNAKMT2A | |
| SCHEMBL8870696 | 0.77 | EGFR (0.47) | TLR7EGFRACP1ALDH1A1HPGD | |
| SCHEMBL8122765 | 0.77 | ACHE (0.34) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8121921 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL7832227 | 0.77 | EGFR (0.43) | TLR7EGFRACP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | claimed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | claimed |
| US-5395937-A | Process for preparing quinoline amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-07 | — | — | US | claimed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | claimed |
| US-8143270-B2 | 2-amino 1H-in-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| EP-1784180-A4 | 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-07-22 | — | — | EP | disclosed |
| US-20090023720-A1 | 2-Amino 1H-Imidazo Ring Systems and Methods | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-22 | — | — | US | disclosed |
| EP-1784180-A2 | 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006029115-A2 | 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5395937-A | Process for preparing quinoline amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023720-A1 | 2-Amino 1H-Imidazo Ring Systems and Methods | IL2, IL2RA, IL4I1 | TLR7 110/4885EGFR 3500/4885ACP1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.