Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833247 | 0.92 | TTPA (0.48) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL8419339 | 0.81 | TTPA (0.54) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL9314929 | 0.78 | TTPA (0.46) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL11705224 | 0.77 | PTGS1 (0.66) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL2059457 | 0.77 | PTGS1 (0.66) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL11701874 | 0.77 | PTGS1 (0.66) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL9252607 | 0.76 | TTPA (0.57) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL9314914 | 0.76 | PSEN1 (0.52) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL9314035 | 0.76 | TTPA (0.47) | TTPAALOX5PSEN1MEN1KMT2A | |
| SCHEMBL9314867 | 0.76 | TTPA (0.44) | TTPAALOX5PSEN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |