Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836510 | 1.00 | MEN1 (0.31) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8801384 | 0.79 | CRBN (0.30) | — | |
| SCHEMBL8801388 | 0.79 | CRBN (0.30) | — | |
| SCHEMBL7837290 | 0.76 | — | — | |
| SCHEMBL8211516 | 0.75 | DPP4 (0.40) | KMT2A | |
| SCHEMBL8211505 | 0.75 | DPP4 (0.40) | MAPT | |
| SCHEMBL7830505 | 0.72 | — | — | |
| SCHEMBL18665213 | 0.72 | — | — | |
| SCHEMBL7830503 | 0.72 | — | — | |
| SCHEMBL2775 | 0.63 | GAA (0.37) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471372-B1 | Novel substituted guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5256679-A | Pesticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0471372-A1 | Novel substituted guanidine derivatives, their preparation and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-19 | — | — | EP | disclosed |