Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801384 | 1.00 | CRBN (0.30) | CRBN | |
| SCHEMBL7837290 | 0.81 | — | — | |
| SCHEMBL7836510 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL7836508 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL7830505 | 0.77 | — | — | |
| SCHEMBL7830503 | 0.77 | — | — | |
| SCHEMBL18665213 | 0.77 | — | — | |
| SCHEMBL3753647 | 0.72 | — | — | |
| SCHEMBL3753641 | 0.72 | — | — | |
| SCHEMBL6560042 | 0.70 | CRBN (0.35) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446913-B1 | Process for the preparation of chlorothiazole derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5633375-A | NONTOXIC TO HUMNAS, ANIMALS, FISH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5489603-A | CONTAINING NITROGEN HETEROCYCLIC RINGS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0493369-B1 | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0665222-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5180833-A | PROCESS FOR THE PREPARATION OF CHLOROTHIAZOLE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| EP-0446913-A1 | Process for the preparation of chlorothiazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0376279-A2 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |