Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211505 | 0.89 | DPP4 (0.40) | DPP4DPP8DPP9BLMNOS1 | |
| SCHEMBL7836508 | 0.75 | MEN1 (0.31) | KMT2A | |
| SCHEMBL7836510 | 0.75 | MEN1 (0.31) | KMT2A | |
| SCHEMBL8773315 | 0.72 | BLM (0.60) | DPP4DPP8DPP9ALOX15BLM | |
| SCHEMBL8801384 | 0.69 | CRBN (0.30) | — | |
| SCHEMBL8801388 | 0.69 | CRBN (0.30) | — | |
| SCHEMBL5574087 | 0.69 | BLM (0.56) | DPP4DPP8DPP9ALOX15BLM | |
| SCHEMBL28528076 | 0.69 | BLM (0.56) | DPP4DPP8DPP9ALOX15BLM | |
| SCHEMBL21035301 | 0.68 | DPP4 (0.57) | DPP4DPP8DPP9ALOX15BLM | |
| SCHEMBL3424069 | 0.68 | DPP4 (0.57) | DPP4DPP8DPP9ALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160126-A | Synthetic Intermediates for the preparation of N, N'-Di-substituted isothiourea derivatives and N-cyclic(methyl)-N'-Substituted isothiourea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| US-5696256-A | CHEMICAL INTERMEDIATE FOR INSECTICIDES; MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0452782-B1 | Novel intermediates for preparing guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| EP-0452782-A1 | Novel intermediates for preparing guanidine derivatives, their preparation and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |