Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398749 | 0.86 | RAB9A (0.56) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL27679373 | 0.85 | HDAC6 (0.58) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1193017 | 0.80 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL651159 | 0.79 | KDR (0.74) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| Propionic Acid SCHEMBL9670302 | 0.79 | HDAC1 (0.64) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9093698 | 0.78 | HDAC6 (0.67) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL14461305 | 0.78 | HDAC1 (0.72) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL27866684 | 0.77 | NPC1 (0.80) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12895711 | 0.77 | RAB9A (0.59) | KDRRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL5797374 | 0.76 | HDAC6 (0.59) | KDRRAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |