Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17731042 | 0.83 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL866389 | 0.74 | ALDH1A1 (0.44) | LMNAALDH1A1TSHR | |
| SCHEMBL28007094 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL29372767 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL10945928 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL22721070 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL29573344 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL24859023 | 0.67 | — | — | |
| SCHEMBL7704495 | 0.67 | — | — | |
| SCHEMBL8010342 | 0.67 | ALDH1A1 (0.44) | LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648763-B1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | AVENTIS PHARMA SA (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5527919-A | Process for the preparation of 1-[(1,1'-biphenyl]-4-YL]-methyl-1H-imidazole-5-carboxylic acids | ROUSSEL UCLAF (FR) | 1996-06-18 | — | — | US | disclosed |
| EP-0648763-A1 | Process for the preparation of sulfur derivatives of imidazole and intermediates obtained | ROUSSEL UCLAF (FR) | 1995-04-19 | — | — | EP | disclosed |