SCHEMBL8010342

SCHEMBL8010342

CON(OC(C)=O)OC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.30
LMNA P02545 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704495 0.94
SCHEMBL866389 0.83 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL28007094 0.80 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL22721070 0.80 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL10945928 0.80 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL29573344 0.80 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL29372767 0.80 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL31147006 0.75 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL9324501 0.73 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL7836639 0.67 LMNA (0.31) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110343062-B Indole derivative containing dithioacetal unit, preparation method and application thereof 贵州大学 2023-03-10 CN disclosed
CN-108368033-B Method for preparing trifloxystrobin GSP作物科学有限公司 2021-05-04 CN disclosed
WO-2017085747-A4 A NOVEL PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN GSP CROP SCIENCE PVT. LTD, (IN) 2017-10-26 WO disclosed
WO-2017085747-A3 A NOVEL PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN GSP CROP SCIENCE PVT. LTD, (IN) 2017-08-03 WO disclosed
WO-2017085747-A2 A NOVEL PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN GSP CROP SCIENCE PVT. LTD, (IN) 2017-05-26 WO disclosed
CN-1145629-C Synthesis of cynnematin �Ҵ���˾ 2004-04-14 CN disclosed
CN-1145628-C Synthesis of cynnematin �Ҵ���˾ 2004-04-14 CN disclosed
CN-1142937-C Antibacterial cephalosporins �Ҵ���˾ 2004-03-24 CN disclosed
CN-1092662-C Cephalosporin synthesis BIOCHEMIE GES GMBH (AT) 2002-10-16 CN disclosed
CN-1344720-A Synthesis of cynnematin BIOCHEMIE GMBH (AT) 2002-04-17 CN disclosed
EP-0979229-A1 2-OXO-1-AZETIDINE SULFONIC ACID DERIVATIVES AS POTENT BETA-LACTAMASE INHIBITORS Naeja Pharmaceutical Inc. (CA) 2000-02-16 EP disclosed
EP-0975587-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
WO-1998047895-A1 2-OXO-1-AZETIDINE SULFONIC ACID DERIVATIVES AS POTENT β-LACTAMASE INHIBITORS NAEJA PHARMACEUTICAL INC. (US) 1998-10-29 WO disclosed
WO-1998043949-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-08 WO disclosed
CN-1186494-A Antibacterial cephalosporins BIOCHEMIE GMBH (AT) 1998-07-01 CN disclosed
CN-1146770-A Cephalosporin synthesis BIOCHEMIE GMBH (AT) 1997-04-02 CN disclosed
WO-1995030639-A1 NOVEL β-METHOXY ACRYLIC ACID DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1995-11-16 WO disclosed
WO-1992021653-A1 PROPENOIC ACID DERIVATIVES SCHERING AGROCHEMICALS LIMITED (GB) 1992-12-10 WO disclosed
CN-1063104-A Trifluoromethyl 1-carbon (1-desulfuration) cephem LILLY CO ELI (US) 1992-07-29 CN disclosed
WO-1992003411-A1 PHENYLOXOACETIC ACID DERIVATIVES SCHERING AGROCHEMICALS LIMITED (GB) 1992-03-05 WO disclosed