Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454178 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL6510223 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL2395983 | 0.76 | GABRA1 (0.36) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL26136210 | 0.74 | GRM2 (0.36) | GABRA1GABRB2MEN1KMT2APKM | |
| SCHEMBL11456733 | 0.68 | GRM2 (0.50) | KMT2ALMNAGRM2 | |
| SCHEMBL253039 | 0.67 | GABRA1 (0.41) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL11777336 | 0.66 | GABRA1 (0.40) | GABRA1GABRB2MEN1KMT2AMAPT | |
| Bicarbonate SCHEMBL28476605 | 0.65 | GABRA1 (0.39) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL4456728 | 0.64 | GABRA1 (0.54) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL5824091 | 0.64 | GABRA1 (0.58) | GABRA1GABRB2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723539-B1 | TRICYCLIC SULFONAMIDE COMPOUNDS USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES | SCHERING CORP (US) | 2001-12-12 | — | — | EP | claimed |