SCHEMBL3454178

SCHEMBL3454178

C=CCc1cccc2c1nnn2O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
POLB P06746 2/20 0.41
ATM Q13315 2/20 0.41
MAPK1 P28482 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 8/20 0.38
KMT2A Q03164 8/20 0.38
PKM P14618 4/20 0.38
ALDH1A1 P00352 4/20 0.37
LMNA P02545 4/20 0.37
MAPT P10636 7/20 0.36
NPSR1 Q6W5P4 3/20 0.36
HTT P42858 3/20 0.36
USP2 O75604 2/20 0.36
HIF1A Q16665 1/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
AKR1B1 P15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7836733 0.81 GABRA1 (0.39) GABRA1GABRB2POLBATMMAPK1
SCHEMBL28854710 0.80 POLB (0.46) POLBATMMAPK1L3MBTL1KMT2A
SCHEMBL29071338 0.78 ATM (0.44) GABRA1GABRB2POLBATMMAPK1
SCHEMBL6510223 0.77 GABRA1 (0.36) GABRA1GABRB2POLBATML3MBTL1
SCHEMBL2395983 0.76 GABRA1 (0.36) GABRA1GABRB2L3MBTL1MEN1KMT2A
SCHEMBL26136210 0.74 GRM2 (0.36) GABRA1GABRB2MEN1KMT2APKM
SCHEMBL3205159 0.74 PLA2G2A (0.31) MEN1KMT2AKDM4E
SCHEMBL3205167 0.73 PLA2G2A (0.32) MAPK1MEN1KMT2AMAPTKDM4E
SCHEMBL378660 0.70 POLB (0.50) POLBATMMAPK1L3MBTL1KMT2A
SCHEMBL7046048 0.69 MAPK1 (0.46) POLBATMMAPK1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1863952-B1 COMPOSITION AND PROCESS FOR PREPARING PROTECTIVE COATINGS ON METAL SUBSTRATES US NAVY (US) 2013-03-06 EP disclosed
US-7811391-B2 Composition and process for preparing protective coatings on metal substrates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-10-12 US disclosed
EP-1863952-A2 COMPOSITION AND PROCESS FOR PREPARING PROTECTIVE COATINGS ON METAL SUBSTRATES The United States of America as Represented by The Secretary of The Navy (US) 2007-12-12 EP disclosed
US-20060237098-A1 Composition and process for preparing protective coatings on metal substrates UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2006-10-26 US disclosed
WO-2006088521-A2 COMPOSITION AND PROCESS FOR PREPARING PROTECTIVE COATINGS ON METAL SUBSTRATES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY, ET AL. (US) 2006-08-24 WO disclosed