Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 10/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093489 | 0.84 | MAP4K4 (0.43) | SYKMAP4K4SUV39H2PDE10AJAK3 | |
| SCHEMBL7836956 | 0.81 | HRH2 (0.39) | SYKMAP4K4SUV39H2PDE10A | |
| SCHEMBL13282845 | 0.77 | OPRK1 (0.40) | KDM4EHPGDKMT2A | |
| SCHEMBL7833450 | 0.76 | KMT2A (0.45) | KDM4EHPGDCYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL7837985 | 0.73 | KMT2A (0.51) | KMT2A | |
| SCHEMBL2092020 | 0.73 | OPRK1 (0.40) | KDM4EHPGDSUV39H2PDE10AKMT2A | |
| SCHEMBL2093718 | 0.73 | OPRK1 (0.40) | KDM4EHPGDSUV39H2PDE10AKMT2A | |
| SCHEMBL7835307 | 0.72 | PRKD3 (0.40) | KDM4EHPGDCYP2C19MAP4K4KMT2A | |
| SCHEMBL761092 | 0.72 | ALDH1A1 (0.39) | KDM4EHPGDCYP2C19KMT2A | |
| SCHEMBL2093348 | 0.70 | SUV39H2 (0.40) | SUV39H2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787726-B1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5817669-A | A COMPOUND CONTAINING 1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0787726-A1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |