Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764407 | 0.84 | LMNA (0.44) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL1466360 | 0.81 | AKR1C3 (0.60) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL6769055 | 0.76 | LMNA (0.71) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL3132223 | 0.75 | AKR1C3 (0.58) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL6773745 | 0.74 | MEN1 (0.53) | LMNASMN1; SMN2HTR6TNFPLK1 | |
| SCHEMBL6768534 | 0.74 | LMNA (0.48) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL7135129 | 0.74 | LMNA (0.48) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL1041051 | 0.73 | LMNA (0.53) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL2511452 | 0.72 | LMNA (0.53) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 | |
| SCHEMBL6765084 | 0.72 | LMNA (0.71) | LMNASMN1; SMN2AKR1C3AKR1C1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069111-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |