Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857392 | 0.88 | PPARG (0.52) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL7823498 | 0.84 | PPARG (0.48) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL1130956 | 0.81 | FFAR1 (0.54) | PPARGFFAR1PPARA | |
| SCHEMBL7824812 | 0.78 | ALOX5 (0.34) | PPARGFFAR1PPARA | |
| SCHEMBL1016492 | 0.77 | PPARG (0.57) | PPARGFFAR1PPARA | |
| SCHEMBL7838282 | 0.77 | PPARG (0.48) | PPARGFFAR1PPARA | |
| SCHEMBL21504716 | 0.75 | MAPT (0.57) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| Hydrochloric Acid SCHEMBL6544449 | 0.75 | PPARG (0.46) | PPARGFFAR1PPARA | |
| SCHEMBL6896704 | 0.75 | PPARG (0.51) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL1130792 | 0.75 | PPARG (0.54) | PPARGFFAR1PPARAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676398-B1 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6117893-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-1022274-A1 | Oxazolidinedione and Thiazolidinedione derivatves, their preparation and their use | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5977365-A | HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |