Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8805271 | 0.80 | PRCP (0.40) | DRD3HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL27546424 | 0.78 | MC4R (0.38) | ESR1ESR2MTNR1BSRD5A1ROCK1 | |
| SCHEMBL1736577 | 0.78 | MAPT (0.50) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8032013 | 0.74 | MAOA (0.56) | ESR1ESR2MTNR1BSRD5A1SLC6A4 | |
| SCHEMBL3592872 | 0.73 | ROCK1 (0.34) | KDM4EMTNR1BMEN1ALDH1A1KMT2A | |
| SCHEMBL1737805 | 0.72 | CCNB2 (0.34) | KDM4EMEN1ALDH1A1KMT2AROCK1 | |
| Hydrochloric Acid SCHEMBL1735825 | 0.71 | CCNB2 (0.33) | KDM4EMEN1ALDH1A1KMT2AROCK1 | |
| SCHEMBL1739182 | 0.71 | CCNB2 (0.33) | KDM4EMEN1ALDH1A1KMT2AROCK1 | |
| SCHEMBL1739177 | 0.71 | CCNB2 (0.33) | KDM4EMEN1ALDH1A1KMT2AROCK1 | |
| SCHEMBL6160361 | 0.71 | ESR1 (0.34) | ESR1ESR2MTNR1BSRD5A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |