Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012740 | 0.86 | MAOA (0.56) | MAOANOTUMSLC6A4HTR2AHTR2C | |
| SCHEMBL8029002 | 0.86 | MAOA (0.56) | MAOANOTUMSLC6A4HTR2AHTR2C | |
| SCHEMBL8030423 | 0.80 | SRD5A1 (0.43) | MAOASRD5A1NOTUMMTNR1BSLC6A4 | |
| SCHEMBL3950020 | 0.79 | MAOA (0.56) | MAOADRD2ESR2HTR2AHTR1A | |
| SCHEMBL8011243 | 0.79 | MAOA (0.56) | MAOASRD5A1DRD2HTR2AHTR2C | |
| SCHEMBL4752284 | 0.79 | MAOA (0.56) | MAOADRD2ESR2HTR2AHTR1A | |
| SCHEMBL20328210 | 0.79 | CYP2D6 (0.47) | MAOASRD5A1NOTUMMTNR1BSLC6A4 | |
| SCHEMBL8019032 | 0.79 | SLC6A4 (0.46) | SRD5A1MTNR1BSLC6A4DRD2 | |
| SCHEMBL8034457 | 0.79 | MAOA (0.64) | MAOADRD2HTR2AHTR2C | |
| SCHEMBL8014211 | 0.78 | MAOA (0.44) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |