Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656596 | 0.83 | MAPT (0.39) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8165766 | 0.83 | MAPT (0.46) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL83319 | 0.83 | NPC1 (0.46) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8164187 | 0.83 | MAPT (0.46) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6967654 | 0.83 | TAAR1 (0.44) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL83780 | 0.82 | PDE3B (0.34) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL83782 | 0.82 | GRIN1 (0.35) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8818079 | 0.82 | NOS3 (0.45) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7830027 | 0.82 | MAPT (0.44) | TAAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL23178714 | 0.81 | ALDH1A1 (0.35) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712394-B1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | DU PONT (US) | 2001-11-28 | — | — | EP | claimed |
| US-5686393-A | Arthropodicidal oxazolines and thiazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-11 | — | — | US | claimed |
| EP-0712394-A1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-05-22 | — | — | EP | claimed |
| WO-1995004726-A1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-16 | — | — | WO | claimed |
| EP-0712394-B1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | DU PONT (US) | 2001-11-28 | — | — | EP | disclosed |
| US-5767281-A | Arthropodicidal oxazolines and thiazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| US-5686393-A | Arthropodicidal oxazolines and thiazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-11 | — | — | US | disclosed |