SCHEMBL7837853

SCHEMBL7837853

CN(C)C1CCN(N2CC[CH]CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL387126 0.75
SCHEMBL3647817 0.70 L3MBTL3 (0.36) L3MBTL3
SCHEMBL7006452 0.70 L3MBTL3 (0.34) L3MBTL3L3MBTL1
SCHEMBL28658161 0.68 L3MBTL3 (0.54) L3MBTL3L3MBTL1
SCHEMBL2380226 0.67 CHRNA7 (0.44) L3MBTL3L3MBTL1
SCHEMBL27985431 0.67 L3MBTL3 (0.42) L3MBTL3L3MBTL1
SCHEMBL46703 0.67 L3MBTL3 (0.42) L3MBTL3L3MBTL1
SCHEMBL4208899 0.66 JAK2 (0.39) L3MBTL3
SCHEMBL23682812 0.65 L3MBTL3 (0.45) L3MBTL3L3MBTL1
SCHEMBL20926955 0.65 L3MBTL3 (0.41) L3MBTL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163239-A1 MODIFIED AMINO-ACID AMIDES AS CGRP ANTAGONISTS Boehringer Ingelheim Pharma KG (DE) 2001-12-19 EP disclosed
WO-2000055154-A1 MODIFIED AMINO-ACID AMIDES AS CGRP ANTAGONISTS BOEHRINGER INGELHEIM PHARMA KG (DE) 2000-09-21 WO disclosed