Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493635 | 0.82 | USP2 (0.49) | PDE5AUSP2TP53SMN1; SMN2MEN1 | |
| SCHEMBL7090211 | 0.82 | PDE5A (0.42) | PDE5AUSP2TP53SMN1; SMN2MEN1 | |
| SCHEMBL7838892 | 0.78 | USP2 (0.35) | USP2MAPK1 | |
| SCHEMBL7092868 | 0.76 | TLR7 (0.45) | TP53SMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL7808088 | 0.74 | PDE5A (0.45) | PDE5AUSP2TP53SMN1; SMN2LMNA | |
| SCHEMBL7966891 | 0.67 | PDE7A (0.50) | PDE5AUSP2SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7093437 | 0.65 | USP2 (0.34) | USP2MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7090330 | 0.65 | USP2 (0.34) | USP2MAPK1 | |
| SCHEMBL7090328 | 0.65 | USP2 (0.34) | USP2MAPK1 | |
| SCHEMBL7660655 | 0.65 | LMNA (0.41) | PDE5AUSP2TP53SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124830-A1 | PYRIMIDIN-4-ENAMINE AS FUNGICIDE | Syngenta Participations AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000031082-A1 | PYRIMIDIN-4-ENAMINE AS FUNGICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-02 | — | — | WO | disclosed |