Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 14/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493635 | 0.79 | USP2 (0.49) | L3MBTL1PDE5AUSP2LMNAMAPT | |
| SCHEMBL8511086 | 0.77 | USP2 (0.44) | PDE7AL3MBTL1PDE4BUSP2PDE4A | |
| SCHEMBL5712364 | 0.76 | ALDH1A1 (0.59) | L3MBTL1PDE5APDE4BUSP2PDE4A | |
| SCHEMBL7891889 | 0.76 | L3MBTL1 (0.62) | PDE7AL3MBTL1PDE4BPDE7BLMNA | |
| SCHEMBL192634 | 0.75 | USP2 (0.45) | PDE7APDE5APDE4BUSP2LMNA | |
| SCHEMBL15049679 | 0.74 | USP2 (0.44) | PDE7APDE5APDE4BUSP2LMNA | |
| SCHEMBL7887669 | 0.73 | USP2 (0.48) | L3MBTL1USP2LMNAMAPTALDH1A1 | |
| SCHEMBL7643515 | 0.72 | USP2 (0.47) | L3MBTL1USP2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7642307 | 0.72 | SMN1; SMN2 (0.54) | L3MBTL1USP2LMNAMAPTALDH1A1 | |
| SCHEMBL192788 | 0.72 | TP53 (0.51) | USP2LMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262058-B1 | Pyrimidin-4-one derivatives as pesticide | SYNGENTA CROP PROTECTION, INC. | 2001-07-17 | — | — | US | disclosed |
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | disclosed |