Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412779 | 0.71 | SLC6A2 (0.47) | CHRNA7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27732339 | 0.70 | TUBB4A (0.52) | CCNCCDK8CHRNA7TUBB4ATUBB | |
| SCHEMBL7617993 | 0.67 | SLC6A2 (0.38) | CCNCCDK8CHRNA7TUBB4ATUBB | |
| SCHEMBL413425 | 0.66 | SLC6A2 (0.61) | CHRNA7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2814112 | 0.65 | OPRM1 (0.54) | OPRM1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL27594512 | 0.63 | TUBB4A (0.52) | CHRNA7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17976396 | 0.63 | MAOB (0.56) | CHRNA7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL413794 | 0.63 | SLC6A2 (0.62) | CHRNA7CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27887307 | 0.63 | TUBB4A (0.70) | CHRNA7TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28265884 | 0.62 | TUBB4A (0.55) | CHRNA7TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | claimed |