Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636053 | 0.90 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7839692 | 0.88 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL7835851 | 0.87 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9279927 | 0.87 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9010398 | 0.86 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7839994 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9010373 | 0.85 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9092277 | 0.85 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9140461 | 0.84 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7838336 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459156-A | Angiotensin converting enzyme inhibitors, hypotensive, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-17 | — | — | US | claimed |
| EP-0513533-B1 | Heterocyclic substituted phenylacetic-acid derivatives, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 2001-11-21 | — | — | EP | disclosed |
| EP-1127880-A2 | Phenylacetic acid derivatives substituted by a heterocycle and their use as A-II antagonists and as inhibitors of smooth muscle cell proliferation | BAYER AG (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |
| US-5459156-A | Angiotensin converting enzyme inhibitors, hypotensive, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0513533-A2 | Heterocyclic substituted phenylacetic-acid derivatives, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |