Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583626 | 0.85 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL6450497 | 0.69 | — | — | |
| SCHEMBL21925017 | 0.69 | — | — | |
| SCHEMBL4406349 | 0.68 | — | — | |
| SCHEMBL25328143 | 0.67 | — | — | |
| SCHEMBL31187948 | 0.66 | — | — | |
| SCHEMBL15670080 | 0.66 | SLC6A12 (0.30) | — | |
| SCHEMBL16090816 | 0.64 | HSD11B1 (0.40) | — | |
| SCHEMBL21013781 | 0.64 | HSD11B1 (0.40) | — | |
| SCHEMBL16064983 | 0.64 | HSD11B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663912-B1 | HETEROCYCLIC ETHER COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LAB (US) | 2001-12-12 | — | — | EP | disclosed |