Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190764 | 0.73 | GRM4 (0.32) | CTSCMEN1KMT2A | |
| SCHEMBL21013695 | 0.73 | GRM4 (0.32) | CTSCMEN1KMT2A | |
| SCHEMBL4186248 | 0.73 | GRM4 (0.32) | CTSCMEN1KMT2A | |
| SCHEMBL16064984 | 0.73 | GRM4 (0.32) | CTSCMEN1KMT2A | |
| SCHEMBL901346 | 0.73 | GRM4 (0.32) | CTSCMEN1KMT2A | |
| SCHEMBL16064857 | 0.73 | GRM4 (0.32) | CTSCMEN1KMT2A | |
| SCHEMBL20586469 | 0.73 | DDB1 (0.33) | — | |
| SCHEMBL15532995 | 0.71 | — | — | |
| SCHEMBL216423 | 0.70 | ALDH1A1 (0.43) | MEN1MAPK1KMT2A | |
| SCHEMBL4877040 | 0.70 | NPSR1 (0.33) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663912-B1 | HETEROCYCLIC ETHER COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LAB (US) | 2001-12-12 | — | — | EP | disclosed |