Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 3/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616000 | 0.92 | OPRM1 (0.41) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL27196327 | 0.92 | OPRM1 (0.41) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL4338991 | 0.92 | OPRM1 (0.41) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL4814544 | 0.92 | OPRM1 (0.41) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL28518503 | 0.92 | OPRM1 (0.41) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL31129088 | 0.90 | DNM1 (0.41) | OPRM1LMNADNM1SMPD1TSHR | |
| Fluoride SCHEMBL28234875 | 0.90 | OPRM1 (0.39) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL28520301 | 0.84 | OPRM1 (0.38) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL29048091 | 0.84 | OPRM1 (0.38) | OPRM1LMNADNM1SMPD1TSHR | |
| SCHEMBL29013718 | 0.83 | DNM1 (0.43) | OPRM1DNM1TSHRFDPSSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634459-B1 | Formulations | MERCK PATENT GMBH (DE) | 2001-04-11 | — | — | EP | disclosed |
| EP-0634459-A2 | Formulations | MERCK PATENT GmbH (DE) | 1995-01-18 | — | — | EP | disclosed |