Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603007 | 0.95 | PPARA (0.59) | PPARAPPARG | |
| SCHEMBL9572631 | 0.91 | CHRM2 (0.47) | PPARAPPARGCYP2D6CHRM2CHRM1 | |
| Butylbenzyl SCHEMBL27552843 | 0.84 | SIGMAR1 (0.47) | PPARAPPARGCHRM2CHRM1 | |
| SCHEMBL2093441 | 0.84 | SOD1 (0.46) | CHRM2CHRM1CHRM3 | |
| SCHEMBL145383 | 0.80 | CHRM2 (0.65) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| Formic Acid Phenyl Ester SCHEMBL27528899 | 0.80 | KCNH2 (0.51) | PPARAPPARG | |
| SCHEMBL9011837 | 0.80 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL5253611 | 0.80 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL8957630 | 0.79 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL5387330 | 0.79 | PPARA (0.56) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |