Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 9/20 | 0.54 |
| ▸ | ACHE | P22303 | 8/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842227 | 0.96 | CA12 (0.63) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7841104 | 0.94 | CA12 (0.63) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7841527 | 0.94 | CA12 (0.57) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7841701 | 0.90 | CA12 (0.61) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7840915 | 0.87 | ACHE (0.55) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7841737 | 0.87 | ACHE (0.51) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7838460 | 0.86 | ACHE (0.68) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL7839666 | 0.86 | RECQL (0.57) | CA12CA9BCHEACHECAPN1 | |
| SCHEMBL12972713 | 0.85 | HSD17B10 (0.66) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL9910052 | 0.85 | HSD17B10 (0.66) | CA12CA9BCHEACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313164-B1 | TO ENHANCE THE ACTIVITY OF GLUTATHIONE RECLUCTASE; FOR THERAPY AND PROPHYLAXIS OF CARTARACTS | SANKYO COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1070710-A2 | Dithiolan derivatives, their preparation and their therapeutic effect | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-6013663-A | CATARACT THERAPY OR PREVENTION | SANKYO COMPANY, LIMITED (JP) | 2000-01-11 | — | — | US | disclosed |
| CN-1208035-A | Dithiolan derivatives, their preparation and their therapeutic effect | SANKYO CO (JP) | 1999-02-17 | — | — | CN | disclosed |