SCHEMBL9910052

SCHEMBL9910052

COC(=O)CCCCC1CCSS1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.66
KMT2A Q03164 2/20 0.66
TARDBP Q13148 2/20 0.66
CYP2C9 P11712 1/20 0.66
MEN1 O00255 1/20 0.66
NR1I2 O75469 1/20 0.66
ALDH1A1 P00352 1/20 0.66
LMNA P02545 1/20 0.66
POLB P06746 1/20 0.66
THRB P10828 1/20 0.66
TSHR P16473 1/20 0.66
ACHE P22303 1/20 0.66
APEX1 P27695 1/20 0.66
RECQL P46063 1/20 0.66
BLM P54132 1/20 0.66
PMP22 Q01453 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
SAE1 Q9UBE0 1/20 0.66
UBA2 Q9UBT2 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12972713 1.00 HSD17B10 (0.66) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7840915 0.90 ACHE (0.55) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7841104 0.89 CA12 (0.63) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7842227 0.89 CA12 (0.63) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL19479306 0.88 TSHR (0.53) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7843232 0.88 PPARG (0.60) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7841701 0.87 CA12 (0.61) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7841737 0.87 ACHE (0.51) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7845468 0.87 RECQL (0.58) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL24601927 0.87 HSD17B10 (0.70) HSD17B10KMT2ATARDBPCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824655-B Andrographolide compound and preparation method and application thereof 沈阳药科大学 2021-09-24 CN claimed
CN-104404098-A Biological preparation method of lipoic acid ENZYMEWORKS INC 2015-03-11 CN claimed
CN-101549153-A Composite and method for self-treating tumor BAOFA YU (CN) 2009-10-07 CN claimed
CN-1273146-C Composition for treating tumor YU BAOFA (US) 2006-09-06 CN claimed
CN-1431909-A Combinations for treating neoplasms YU BAOFA (US) 2003-07-23 CN claimed
US-12043865-B2 Genetic probe for the detection of a single nucleotide polymorphism (SNP) or a single nucleotide modification of a target nucleic acid THE UNIVERSITY OF BIRMINGHAM (GB) 2024-07-23 US disclosed
WO-2024134266-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF DERMAL AND OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2024-06-27 WO disclosed
US-20230346744-A1 SULFUR-CONTAINING COMPOUND USEFUL FOR TREATING OR PREVENTING PRESBYOPIA SANTEN PHARMACEUTICAL CO., LTD. (JP) 2023-11-02 US disclosed
US-20230346744-A1 SULFUR-CONTAINING COMPOUND USEFUL FOR TREATING OR PREVENTING PRESBYOPIA SANTEN PHARMACEUTICAL CO., LTD. (JP) 2023-11-02 US disclosed
US-20230346744-A1 SULFUR-CONTAINING COMPOUND USEFUL FOR TREATING OR PREVENTING PRESBYOPIA SANTEN PHARMACEUTICAL CO., LTD. (JP) 2023-11-02 US disclosed
EP-4159209-A1 SULFUR-CONTAINING COMPOUND USEFUL FOR TREATING OR PREVENTING PRESBYOPIA Santen Pharmaceutical Co., Ltd. (JP) 2023-04-05 EP disclosed
CN-115515570-A Sulfur-containing compounds useful for the treatment or prevention of presbyopia 参天制药株式会社 2022-12-23 CN disclosed
US-7615775-B2 Semiconductor apparatus and process for fabricating same SONY CORPORATION (JP) 2009-11-10 US disclosed
US-7615775-B2 Semiconductor apparatus and process for fabricating same SONY CORPORATION (JP) 2009-11-10 US disclosed
CN-101549153-A Composite and method for self-treating tumor BAOFA YU (CN) 2009-10-07 CN disclosed
CN-1273146-C Composition for treating tumor YU BAOFA (US) 2006-09-06 CN disclosed
CN-1680364-A Method for producing lipoic acid and dihydrolipoic acid BASF AG (DE) 2005-10-12 CN disclosed
CN-1218945-C Preparation method of lipoic acid and dihydrolipoic acid BASF AG (DE) 2005-09-14 CN disclosed
CN-1444580-A Preparation method of lipoic acid and dihydrolipoic acid BASF AG (DE) 2003-09-24 CN disclosed
CN-1431909-A Combinations for treating neoplasms YU BAOFA (US) 2003-07-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346744-A1 SULFUR-CONTAINING COMPOUND USEFUL FOR TREATING OR PREVENTING PRESBYOPIA CBS, PSEN1, PSEN2 HSD17B10 1875/4885KMT2A 3172/4885TARDBP 1808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.