Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468599 | 0.82 | MEN1 (0.38) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL7617127 | 0.78 | HNF4A (0.32) | — | |
| SCHEMBL6726208 | 0.76 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL6203050 | 0.74 | KDM4E (0.44) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL6184322 | 0.73 | KDM4E (0.43) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL27527651 | 0.70 | MEN1 (0.40) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL8458842 | 0.70 | MEN1 (0.38) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL6349021 | 0.70 | ALOX5 (0.42) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL8101913 | 0.69 | RARB (0.53) | ALDH1A1RARARARBRARGAKR1B1 | |
| SCHEMBL6344023 | 0.69 | SMN1; SMN2 (0.33) | SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712853-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| EP-0712853-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |