Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 4/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059932 | 1.00 | SMPD1 (0.56) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL2514364 | 0.85 | SMPD1 (0.69) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL2370055 | 0.85 | SMPD1 (0.69) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL11619477 | 0.85 | SMPD1 (0.69) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL28470942 | 0.85 | SMPD1 (0.69) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL3775302 | 0.85 | FDPS (0.40) | SMPD1PTPN1FDPSLPAR3LPAR1 | |
| Ammonia Solution, Strong SCHEMBL28408668 | 0.84 | SMPD1 (0.67) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL28701575 | 0.84 | SMPD1 (0.67) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL8682289 | 0.83 | SMPD1 (0.66) | SMPD1PTPN1FDPSS1PR2S1PR1 | |
| SCHEMBL21177985 | 0.83 | SMPD1 (0.56) | SMPD1PTPN1FDPSS1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109817-A1 | PHOSPHOHALOHYDRINS, METHOD FOR MAKING SAME AND USES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012516-A1 | PHOSPHOHALOHYDRINS, METHOD FOR MAKING SAME AND USES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2000-03-09 | — | — | WO | disclosed |