Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840417 | 0.85 | SMPD1 (0.56) | FDPSSMPD1PTPN1LPAR1LPAR3 | |
| SCHEMBL4059932 | 0.85 | SMPD1 (0.56) | FDPSSMPD1PTPN1LPAR1LPAR3 | |
| SCHEMBL2676632 | 0.83 | SMPD1 (0.50) | FDPSSMPD1METAP1PTPN1LPAR1 | |
| SCHEMBL29790860 | 0.82 | FDPS (0.41) | FDPSSMPD1METAP1BTN3A1PTPN1 | |
| SCHEMBL5479750 | 0.80 | BTN3A1 (0.36) | FDPSSMPD1BTN3A1BLMTDP1 | |
| SCHEMBL27481354 | 0.80 | GABBR2 (0.36) | FDPSBTN3A1BLMTDP1 | |
| SCHEMBL29790857 | 0.80 | METAP1 (0.42) | FDPSSMPD1METAP1BTN3A1PTPN1 | |
| SCHEMBL1203388 | 0.78 | SMPD1 (0.39) | FDPSSMPD1METAP1BTN3A1PTPN1 | |
| SCHEMBL27594540 | 0.78 | FDPS (0.39) | FDPSSMPD1METAP1BTN3A1PTPN1 | |
| SCHEMBL27508185 | 0.77 | BLM (0.34) | FDPSSMPD1BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086617-A2 | TREATMENT | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2010-08-05 | — | — | WO | disclosed |