Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848088 | 0.98 | TSHR (0.59) | TSHRLTA4HSMPD1KMT2APLA2G4B | |
| SCHEMBL7848627 | 0.95 | TSHR (0.50) | TSHRLTA4HSMPD1KMT2APLA2G4B | |
| SCHEMBL7848585 | 0.90 | KMT2A (0.50) | TSHRLTA4HKMT2AGPBAR1NR1H4 | |
| SCHEMBL3444130 | 0.83 | ALDH1A1 (0.53) | KMT2ATHRATHRB | |
| SCHEMBL6545404 | 0.82 | TP53 (0.53) | TSHRLTA4HKMT2ATHRB | |
| SCHEMBL11663051 | 0.82 | TSHR (0.72) | TSHRLTA4HSMPD1KMT2APLA2G4B | |
| SCHEMBL6677146 | 0.80 | TSHR (0.76) | TSHRLTA4HSMPD1PLA2G4BGPBAR1 | |
| SCHEMBL4208924 | 0.80 | TSHR (0.76) | TSHRLTA4HSMPD1PLA2G4BGPBAR1 | |
| SCHEMBL17138169 | 0.80 | TSHR (0.76) | TSHRLTA4HSMPD1PLA2G4BGPBAR1 | |
| SCHEMBL3905859 | 0.80 | TSHR (0.76) | TSHRLTA4HSMPD1PLA2G4BGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |