Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840499 | 0.95 | TSHR (0.57) | TSHRKMT2ALTA4HTHRBPLA2G4B | |
| SCHEMBL7848088 | 0.93 | TSHR (0.59) | TSHRKMT2ALTA4HTHRBPLA2G4B | |
| SCHEMBL7848585 | 0.91 | KMT2A (0.50) | TSHRKMT2ALTA4HGPBAR1CYSLTR1 | |
| SCHEMBL6545404 | 0.84 | TP53 (0.53) | TSHRKMT2ALTA4HCYP1A2CYP2C19 | |
| SCHEMBL4397448 | 0.81 | TSHR (0.63) | TSHRKMT2ALTA4HTLR4TLR2 | |
| SCHEMBL3444130 | 0.81 | ALDH1A1 (0.53) | KMT2ATHRBSMN1; SMN2 | |
| SCHEMBL3135728 | 0.80 | LTA4H (0.52) | TSHRLTA4HSMN1; SMN2 | |
| 1-Butyloxy-3-Propoxybenzene SCHEMBL3390925 | 0.77 | TSHR (0.59) | TSHRKMT2ALTA4HTLR4TLR2 | |
| SCHEMBL5246109 | 0.77 | DHFR (0.48) | TSHRKMT2ALTA4HPLA2G4B | |
| SCHEMBL197632 | 0.77 | KMT2A (0.76) | TSHRKMT2ALTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |