Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829366 | 0.83 | ADRB2 (0.51) | ADRB2HTTTAAR1HSD17B10CYP1A2 | |
| SCHEMBL7839860 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2TAAR1 | |
| SCHEMBL8532601 | 0.77 | ADRB2 (0.75) | ADRB2 | |
| SCHEMBL10499469 | 0.77 | KMT2A (0.66) | ALDH1A1LMNAHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL10452367 | 0.77 | KMT2A (0.66) | ALDH1A1LMNAHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL8673879 | 0.77 | ADRB2 (0.53) | ADRB2 | |
| SCHEMBL8532543 | 0.77 | ADRB2 (0.69) | ADRB2 | |
| SCHEMBL7295271 | 0.72 | SLC2A1 (0.61) | ALDH1A1KDM4EHPGD | |
| SCHEMBL8671939 | 0.72 | ADRB2 (0.51) | ADRB2 | |
| Hydrochloric Acid SCHEMBL8899662 | 0.71 | ADRB2 (0.63) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558677-B1 | BIOLOGICALLY ACTIVE AMINES | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5763465-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| US-5648370-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-07-15 | — | — | US | disclosed |