Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220817 | 0.78 | SLC7A5 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL23421123 | 0.78 | SLC7A5 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL27732246 | 0.73 | SLC7A5 (0.35) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL5331947 | 0.71 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL889024 | 0.71 | HRH4 (0.55) | NR1H4CYP1A2CYP2C9HSD17B10NPSR1 | |
| SCHEMBL31037762 | 0.70 | P4HTM (0.63) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL18782928 | 0.69 | CYP1A2 (0.43) | NR1H4PDE9ACYP1A2CYP2C9HSD17B10 | |
| SCHEMBL5201259 | 0.68 | PDE9A (0.40) | NR1H4PDE9ACYP1A2CYP2C9HSD17B10 | |
| SCHEMBL16931563 | 0.68 | NR1H2 (0.39) | RXRANR1H2NR1H3 | |
| SCHEMBL1078758 | 0.68 | IGF1R (0.41) | CYP1A2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140942-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039130-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2000-07-06 | — | — | WO | disclosed |