Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 12/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849344 | 0.81 | ALDH1A1 (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL7841006 | 0.71 | NR1H4 (0.40) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL2213943 | 0.69 | HCAR2 (0.56) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1078758 | 0.68 | IGF1R (0.41) | ALDH1A1IGF1R | |
| SCHEMBL23421123 | 0.67 | SLC7A5 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL29220817 | 0.67 | SLC7A5 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL14334534 | 0.66 | L3MBTL1 (0.31) | — | |
| SCHEMBL2429665 | 0.66 | NPC1 (0.45) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL991875 | 0.66 | GABRG2 (0.42) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL26102097 | 0.65 | ALDH1A1 (0.36) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812445-A1 | PHARMACEUTICAL COMPOUNDS | Piramed Limited (GB) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006046031-A1 | PHARMACEUTICAL COMPOUNDS | PIRAMED LIMITED (GB) | 2006-05-04 | — | — | WO | disclosed |