Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055004 | 0.92 | MEN1 (0.71) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL7539086 | 0.84 | MEN1 (0.62) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL9416238 | 0.82 | MEN1 (0.59) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL10391045 | 0.82 | KDM4E (0.55) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL38471077 | 0.82 | KDM4E (0.55) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL7544097 | 0.80 | MEN1 (0.56) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL982547 | 0.78 | NR4A1 (0.54) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL31396473 | 0.78 | NR4A1 (0.54) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL31150345 | 0.78 | DEGS1 (0.78) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL368228 | 0.78 | DEGS1 (0.78) | MEN1KMT2AHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288232-B2 | REACTION OF ACETYLNAPHTHALIC ANHYDRIDE AND ALDEHYDE IN THE PRESENCE OF AQUEOUS BASE AND BOILING IN THE PRESENCE OF ANILINE COMPOUND | EMAGIN CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | AHR, NAT1, ARSA | MEN1 4783/4885KMT2A 2529/4885HPGD 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.