Sugi Predict

Sugi Predict / Compounds / SCHEMBL982547

SCHEMBL982547

SCHEMBL982547

CC(=O)c1ccc(C(=O)O)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A1 P22736 1/20 0.54
▸ NR4A2 P43354 1/20 0.54
▸ NR4A3 Q92570 1/20 0.54
▸ AKR1C4 P17516 1/20 0.51
▸ AKR1C3 P42330 1/20 0.51
▸ AKR1C2 P52895 1/20 0.51
▸ AKR1C1 Q04828 1/20 0.51
▸ ALDH1A1 P00352 2/20 0.50
▸ WDR5 P61964 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ KDM4E B2RXH2 3/20 0.48
▸ HPGD P15428 2/20 0.48
▸ BRD4 O60885 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ TSHR P16473 2/20 0.48
▸ LDHA P00338 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ ATIC P31939 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31396473 1.00 NR4A1 (0.54) NR4A1NR4A2NR4A3AKR1C4AKR1C3
SCHEMBL26253880 0.91 NR4A1 (0.59) NR4A1NR4A2NR4A3AKR1C4AKR1C3
SCHEMBL10391045 0.91 KDM4E (0.55) AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1
SCHEMBL38471077 0.91 KDM4E (0.55) AKR1C4AKR1C3AKR1C2AKR1C1ALDH1A1
SCHEMBL30838412 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL29406630 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL28798 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL30838413 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL7738797 0.85 NR4A1 (0.62) NR4A1NR4A2NR4A3ALDH1A1WDR5
Hydrochloric Acid SCHEMBL4429797 0.85 NR4A1 (0.62) NR4A1NR4A2NR4A3ALDH1A1WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384028-A Synthesis method of 4-acetyl-1-naphthoic acid 济南久隆医药科技有限公司 2024-01-12 — — CN claimed
CN-116253658-B Synthesis method of aforana intermediate 济南久隆医药科技有限公司 2023-08-11 — — CN claimed
CN-116253658-A Synthesis method of aforana intermediate 济南久隆医药科技有限公司 2023-06-13 — — CN claimed
CN-111333512-A Preparation of Aforana key intermediate 4-acetyl-1-naphthoate 江苏君若药业有限公司 2020-06-26 — — CN claimed
CN-117384028-B Synthesis method of 4-acetyl-1-naphthoic acid 济南久隆医药科技有限公司 2025-02-14 — — CN disclosed
CN-117384028-A Synthesis method of 4-acetyl-1-naphthoic acid 济南久隆医药科技有限公司 2024-01-12 — — CN disclosed
US-20230352749-A1 POSITIVE ELECTRODE FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY COMPRISING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-11-02 — — US disclosed
US-20230303482-A1 METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE E.I. DU PONT DE NEMOURS AND COMPANY 2023-09-28 — — US disclosed
US-20230303482-A1 METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE E.I. DU PONT DE NEMOURS AND COMPANY 2023-09-28 — — US disclosed
EP-4239728-A1 POSITIVE ELECTRODE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING SAME Samsung SDI Co., Ltd. (KR) 2023-09-06 — — EP disclosed
EP-3150575-B1 METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE DU PONT (US) 2023-08-09 — — EP disclosed
EP-3150575-B1 METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE DU PONT (US) 2023-08-09 — — EP disclosed
CN-101990530-A Process for the preparation of 3-trifluoromethyl chalcones DU PONT 2011-03-23 — — CN disclosed
US-20110009638-A1 METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES E.I. DU PONT DE NEMOURS AND COMPANY (DE) 2011-01-13 — — US disclosed
EP-2260016-A2 METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES E. I. du Pont de Nemours and Company (US) 2010-12-15 — — EP disclosed
CN-101855215-A For preparing 5-haloalkyl-4 DU PONT 2010-10-06 — — CN disclosed
US-20100249424-A1 METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES E.I.DUPONT DE NEMOURS AND COMPANY (US) 2010-09-30 — — US disclosed
EP-2176244-A2 METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES E. I. du Pont de Nemours and Company (US) 2010-04-21 — — EP disclosed
WO-2009126668-A2 METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-15 — — WO disclosed
WO-2009025983-A2 METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303482-A1 METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE NAAA, SAT1, NAA15 NR4A1 3581/4885NR4A2 3416/4885NR4A3 4224/4885
US-20110009638-A1 METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES NR3C2, CYP4A11, RAE1 NR4A1 139/4885NR4A2 456/4885NR4A3 245/4885
US-20100249424-A1 METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES PRDX2, PRXL2A, PRDX1 NR4A1 3764/4885NR4A2 2201/4885NR4A3 3155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.