SCHEMBL649980

SCHEMBL649980

O=C(O)c1ccc(C(=O)O)c(Oc2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.66
AKR1C3 P42330 1/20 0.58
SRD5A2 P31213 3/20 0.53
POLB P06746 2/20 0.53
KDM4E B2RXH2 1/20 0.51
HPSE Q9Y251 1/20 0.49
NR1H4 Q96RI1 1/20 0.48
CTNNB1 P35222 1/20 0.47
MBTD1 Q05BQ5 1/20 0.47
L3MBTL3 Q96JM7 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CASP6 P55212 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10485517 0.98 TTR (0.64) TTRAKR1C3SRD5A2POLBKDM4E
Hydrochloric Acid SCHEMBL28567730 0.98 TTR (0.64) TTRAKR1C3SRD5A2POLBKDM4E
Hydrochloric Acid SCHEMBL9672161 0.95 TTR (0.60) TTRAKR1C3SRD5A2POLBKDM4E
SCHEMBL11322194 0.91 TTR (0.54) TTRAKR1C3SRD5A2POLBKDM4E
SCHEMBL30497476 0.91 TTR (0.54) TTRAKR1C3SRD5A2POLBKDM4E
SCHEMBL28045609 0.90 AKR1C3 (0.64) TTRAKR1C3POLBKDM4EHPSE
SCHEMBL15855781 0.88 CTNNB1 (0.65) TTRAKR1C3SRD5A2POLBCTNNB1
SCHEMBL9807221 0.86 TTR (0.53) TTRSRD5A2POLBL3MBTL1
SCHEMBL29038528 0.86 HTT (0.59) TTRPOLBKDM4E
SCHEMBL184391 0.86 TTR (0.70) TTRAKR1C3SRD5A2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116285195-A High-wear-resistance sheath material for locomotive cable and preparation method thereof 江苏馨德高分子材料股份有限公司 2023-06-23 CN claimed
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP claimed
US-5162483-A To provide heat/oxidation resistance and discoloration inhibition HUELS AKTIENGESELLSCHAFT (DE) 1992-11-10 US claimed
EP-0284726-B1 AROMATIC POLYESTER BASED ON PHENOXYTEREPHTHALIC ACID, PROCESS FOR ITS PREPARATION AND ITS USE HÜLS AKTIENGESELLSCHAFT (DE) 1991-10-23 EP claimed
US-4968737-A Molding compounds comprising a thermoplastically processible aromatic polyamide HUELS AKTIENGESELLSCHAFT (DE) 1990-11-06 US claimed
US-4952662-A Molding compounds comprising a thermoplastically processible, aromatic polyamide Huels Aktiengaellscaft (DE) 1990-08-28 US claimed
US-4843140-A MOLDING MATERIALS HUELS AKTIENGESELLSCHAFT (DE) 1989-06-27 US claimed
EP-0284726-A2 Aromatic polyester based on phenoxyterephthalic acid, process for its preparation and its use HÜLS AKTIENGESELLSCHAFT (DE) 1988-10-05 EP claimed
JP-3095231-A None JP disclosed
JP-60069132-A None JP disclosed
US-20260103594-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-3 BASF SE (DE) 2026-04-16 US disclosed
US-20260103596-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-1 BASF SE (DE) 2026-04-16 US disclosed
EP-4536741-B1 RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND BASF SE (DE) 2026-01-21 EP disclosed
US-20250320346-A1 RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND BASF SE (DE) 2025-10-16 US disclosed
EP-0120502-A2 Process for treating polyarylates AMOCO CORPORATION (US) 1984-10-03 EP disclosed
EP-0091602-A1 Process for preparing polyarylates AMOCO CORPORATION (US) 1983-10-19 EP disclosed
US-4386186-A IN PRESENCE OF THERMOPLASTIC RESIN; REDUCED VISCOSITY UNION CARBIDE CORPORATION (US) 1983-05-31 US disclosed
EP-0058403-A2 Flame retardant polyarylate compositions AMOCO CORPORATION (US) 1982-08-25 EP disclosed
EP-0052377-A1 Polyarylate blends with ethylene-alkyl acrylate copolymers UNION CARBIDE CORPORATION (US) 1982-05-26 EP disclosed
JP-H00395231-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103594-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-3 SMC3, ASIC3, PUF60 TTR 2830/4885AKR1C3 2221/4885SRD5A2 976/4885
US-20260103596-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-1 PUF60, PHPT1, P4HA1 TTR 3668/4885AKR1C3 1574/4885SRD5A2 759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.