Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38471077 | 0.87 | KDM4E (0.55) | KDM4EBRD4ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10391045 | 0.87 | KDM4E (0.55) | KDM4EBRD4ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL982076 | 0.86 | BRD4 (0.53) | KDM4EBRD4ALDH1A1HPGDTSHR | |
| SCHEMBL31049726 | 0.86 | BRD4 (0.53) | KDM4EBRD4ALDH1A1HPGDTSHR | |
| SCHEMBL31049722 | 0.86 | BRD4 (0.53) | KDM4EBRD4ALDH1A1HPGDTSHR | |
| SCHEMBL28416763 | 0.81 | TSHR (0.63) | KDM4EALDH1A1GAATSHRPOLB | |
| SCHEMBL31284375 | 0.81 | NR4A1 (0.52) | KDM4EALDH1A1HPGDL3MBTL1TSHR | |
| SCHEMBL9166724 | 0.79 | IDO1 (0.54) | KDM4EGAATSHRMAPTKMT2A | |
| SCHEMBL982547 | 0.78 | NR4A1 (0.54) | KDM4EBRD4ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL31396473 | 0.78 | NR4A1 (0.54) | KDM4EBRD4ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288232-B2 | REACTION OF ACETYLNAPHTHALIC ANHYDRIDE AND ALDEHYDE IN THE PRESENCE OF AQUEOUS BASE AND BOILING IN THE PRESENCE OF ANILINE COMPOUND | EMAGIN CORPORATION | 2001-09-11 | — | — | US | claimed |
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | claimed |
| US-6288232-B2 | REACTION OF ACETYLNAPHTHALIC ANHYDRIDE AND ALDEHYDE IN THE PRESENCE OF AQUEOUS BASE AND BOILING IN THE PRESENCE OF ANILINE COMPOUND | EMAGIN CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | AHR, NAT1, ARSA | KDM4E 3163/4885BRD4 1840/4885ALDH1A1 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.