Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 9/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784113 | 1.00 | BDKRB1 (0.40) | BDKRB1KDM4DF10MEN1KMT2A | |
| SCHEMBL785798 | 0.95 | F10 (0.38) | BDKRB1F10MEN1KMT2AROCK2 | |
| SCHEMBL785047 | 0.95 | BDKRB1 (0.41) | BDKRB1KDM4DF10MEN1KMT2A | |
| SCHEMBL785292 | 0.91 | F10 (0.39) | BDKRB1F10ROCK2 | |
| SCHEMBL27902576 | 0.89 | SMO (0.39) | F10ROCK2 | |
| SCHEMBL785887 | 0.89 | TRPV1 (0.42) | F10 | |
| SCHEMBL785833 | 0.89 | JAK2 (0.40) | F10 | |
| SCHEMBL785312 | 0.89 | P2RX7 (0.39) | F10ROCK2 | |
| SCHEMBL784693 | 0.88 | F10 (0.38) | BDKRB1F10ROCK2 | |
| SCHEMBL785478 | 0.87 | BDKRB1 (0.40) | BDKRB1KDM4DF10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | claimed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | BDKRB1 1/4885KDM4D 1153/4885F10 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.