Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540804 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9874499 | 0.87 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9873526 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9443313 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9853647 | 0.86 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9873468 | 0.86 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9871361 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9873306 | 0.84 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9873087 | 0.84 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9874069 | 0.84 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | claimed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | claimed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | claimed |
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |