Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393351 | 0.90 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL9853665 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9853658 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL9313883 | 0.88 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9854234 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9194965 | 0.87 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9031623 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9874393 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7841529 | 0.86 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9198359 | 0.85 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | claimed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |
| EP-0415886-A2 | Aza compounds | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |