Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136278 | 0.85 | KDM4E (0.34) | KDM4EHPGDHSD17B10PTK2NOTUM | |
| SCHEMBL8128418 | 0.85 | KDM4E (0.33) | KDM4EHPGDHSD17B10PTK2NOTUM | |
| SCHEMBL7843121 | 0.84 | TSHR (0.39) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL8135012 | 0.82 | BRD4 (0.41) | KDM4EHPGDHSD17B10GAAMEN1 | |
| SCHEMBL7841597 | 0.78 | KDM4E (0.33) | KDM4EPTK2ALDH1A1RXRARXRB | |
| SCHEMBL8871666 | 0.78 | KDM4E (0.34) | KDM4EGAAALDH1A1RXRARXRB | |
| SCHEMBL8871664 | 0.78 | KDM4E (0.34) | KDM4EGAAALDH1A1RXRARXRB | |
| SCHEMBL8317930 | 0.78 | ALDH1A1 (0.34) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6725377 | 0.76 | ALDH1A1 (0.32) | KDM4EALDH1A1HTTMAPT | |
| SCHEMBL8562161 | 0.75 | KDM4E (0.31) | KDM4EHPGDHSD17B10GAANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297196-B1 | HETEROCYCLIC COMPOUNDS WITH KETONE GROUPS AND OXIMES, PHOSPHONATES OR PHOSPHATES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-02 | — | — | US | disclosed |
| EP-1109807-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-06-27 | — | — | EP | disclosed |
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| WO-2000014087-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-03-16 | — | — | WO | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |