Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 11/20 | 0.79 |
| ▸ | PRKCA | P17252 | 2/20 | 0.79 |
| ▸ | JAK3 | P52333 | 8/20 | 0.65 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.58 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | PRKCG | P05129 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | CDK4 | P11802 | 1/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.58 |
| ▸ | PRKACA | P17612 | 1/20 | 0.58 |
| ▸ | PRKACG | P22612 | 1/20 | 0.58 |
| ▸ | PRKACB | P22694 | 1/20 | 0.58 |
| ▸ | CCND1 | P24385 | 1/20 | 0.58 |
| ▸ | PRKCH | P24723 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060142 | 0.89 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7840920 | 0.89 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7831655 | 0.86 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7841411 | 0.86 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7841496 | 0.86 | PRKCB (0.75) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7831858 | 0.86 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7830740 | 0.85 | PRKCB (0.80) | PRKCBPRKCAJAK3JAK1JAK2 | |
| SCHEMBL7841254 | 0.83 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 | |
| SCHEMBL7842735 | 0.83 | PRKCB (1.00) | PRKCBPRKCAJAK3JAK1JAK2 | |
| SCHEMBL7841077 | 0.83 | PRKCB (1.00) | PRKCBPRKCAJAK3CAMK2DPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | claimed |
| WO-2013029043-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |