Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 15/20 | 0.36 |
| ▸ | BRAF | P15056 | 15/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240473 | 0.87 | CCR1 (0.33) | KDM4CKDM6BKDM5AKDM4DKDM5B | |
| SCHEMBL7843005 | 0.85 | CYP17A1 (0.41) | BRAF | |
| SCHEMBL7853175 | 0.84 | KDM4E (0.40) | DYRK1ACCR1CCR5CCR8 | |
| SCHEMBL7238742 | 0.82 | CCR1 (0.38) | DYRK1ACCR1CCR5CCR8 | |
| SCHEMBL3778074 | 0.78 | POLB (0.43) | RAF1 | |
| SCHEMBL3778070 | 0.78 | POLB (0.43) | RAF1 | |
| SCHEMBL13785800 | 0.78 | POLB (0.43) | RAF1 | |
| SCHEMBL7845048 | 0.78 | KDR (0.41) | — | |
| SCHEMBL7846741 | 0.78 | AAK1 (0.38) | CCR1CCR5CCR8 | |
| SCHEMBL17560319 | 0.78 | RAB9A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |