Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20332457 | 0.80 | ESR1 (0.42) | ESR1ESR2PPARG | |
| SCHEMBL2655434 | 0.80 | FFAR1 (0.35) | ESR1ESR2PPARG | |
| SCHEMBL7839995 | 0.76 | ESR1 (0.35) | ESR1ESR2PPARG | |
| SCHEMBL30467048 | 0.76 | ESR1 (0.35) | ESR1ESR2PPARG | |
| SCHEMBL25253178 | 0.73 | PTGS2 (0.40) | — | |
| SCHEMBL28312128 | 0.72 | CYP4A11 (0.48) | — | |
| SCHEMBL30467054 | 0.71 | ESR1 (0.33) | ESR1ESR2PPARG | |
| SCHEMBL30467049 | 0.71 | ESR1 (0.33) | ESR1ESR2PPARG | |
| SCHEMBL20332538 | 0.71 | ESR1 (0.33) | ESR1ESR2PPARG | |
| SCHEMBL29694640 | 0.70 | ESR1 (0.40) | ESR1ESR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579733-B1 | THIAZOLIDINEDIONE DERIVATIVES, PRODUCTION AND USE THEREOF | UPJOHN CO (US) | 2001-06-20 | — | — | EP | disclosed |
| US-5441971-A | Antidiabetic agents | THE UPJOHN COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0579733-A1 | THIAZOLIDINEDIONE DERIVATIVES, PRODUCTION AND USE THEREOF | PHARMACIA & UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018501-A1 | THIAZOLIDINEDIONE DERIVATIVES, PRODUCTION AND USE THEREOF | THE UPJOHN COMPANY (US) | 1992-10-29 | — | — | WO | disclosed |