Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282249 | 0.73 | CYP3A4 (0.42) | CYP2D6TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6615572 | 0.73 | TAS1R3 (0.43) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL6014481 | 0.69 | TAAR1 (0.58) | CYP2D6TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2268770 | 0.67 | CYP3A4 (0.56) | CYP2D6CYP3A4CYP1A2CYP2C9ALOX15 | |
| SCHEMBL172849 | 0.66 | CYP1A2 (0.55) | CYP2D6CYP3A4CYP1A2CYP2C9ALOX15 | |
| SCHEMBL18029886 | 0.65 | CYP3A4 (0.47) | CYP2D6CYP3A4CYP1A2CYP2C9ALOX15 | |
| SCHEMBL31544886 | 0.65 | TAAR1 (0.56) | TAAR1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL772701 | 0.64 | HSP90AA1 (0.51) | CYP2D6CYP3A4CYP1A2CYP2C9ALOX15 | |
| SCHEMBL14284021 | 0.63 | CYP3A4 (0.46) | CYP2D6CYP3A4CYP1A2CYP2C9ALOX15 | |
| SCHEMBL9908794 | 0.63 | CYP3A4 (0.46) | CYP2D6CYP3A4CYP1A2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054673-A4 | BENZOXAZINE COMPOUNDS FOR ENHANCING SYNAPTIC RESPONSE | CORTEX PHARMA INC (US) | 2001-07-18 | — | — | EP | disclosed |
| EP-1054673-A1 | BENZOXAZINE COMPOUNDS FOR ENHANCING SYNAPTIC RESPONSE | CORTEX PHARMACEUTICALS, INC. (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999033469-A1 | BENZOXAZINE COMPOUNDS FOR ENHANCING SYNAPTIC RESPONSE | CORTEX PHARMACEUTICALS, INC. (US) | 1999-07-08 | — | — | WO | disclosed |