Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 5/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6340786 | 0.99 | DRD2 (0.39) | DRD2DRD4OPRM1DRD3FDPS | |
| SCHEMBL6341497 | 0.78 | SRC (0.45) | GRM2GRM3KMT2AALDH1A1NPC1 | |
| SCHEMBL6344201 | 0.78 | SRC (0.45) | GRM2GRM3KMT2AALDH1A1NPC1 | |
| SCHEMBL7441576 | 0.76 | GRM2 (0.53) | GRM2GRM3ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL11088109 | 0.76 | GRM2 (0.53) | GRM2GRM3ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL8219953 | 0.76 | GRM2 (0.53) | GRM2GRM3ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL28307236 | 0.74 | GRM2 (0.47) | GRM2GRM3ALDH1A1SMN1; SMN2HIF1A | |
| Hydrochloric Acid SCHEMBL6340862 | 0.73 | DRD4 (0.46) | DRD2DRD4OPRM1DRD3FDPS | |
| SCHEMBL27463604 | 0.72 | TSHR (0.49) | GRM2GRM3KMT2AALDH1A1NPC1 | |
| SCHEMBL6345448 | 0.72 | TSHR (0.49) | GRM2GRM3KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832066-B1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-1996039385-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER INC. (US) | 1996-12-12 | — | — | WO | disclosed |