Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 16/20 | 0.89 |
| ▸ | PRKCB | P05771 | 15/20 | 0.89 |
| ▸ | PRKCE | Q02156 | 11/20 | 0.89 |
| ▸ | PRKACA | P17612 | 3/20 | 0.64 |
| ▸ | PRKACG | P22612 | 3/20 | 0.64 |
| ▸ | PRKACB | P22694 | 3/20 | 0.64 |
| ▸ | PIM1 | P11309 | 2/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.61 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.61 |
| ▸ | PRKCH | P24723 | 3/20 | 0.61 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.59 |
| ▸ | CDK1 | P06493 | 3/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.59 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838765 | 0.94 | PRKCA (0.88) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7830800 | 0.94 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7843214 | 0.91 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7842250 | 0.90 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7843888 | 0.86 | PRKCA (0.81) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7831816 | 0.85 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7841721 | 0.84 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7842285 | 0.83 | PRKCB (1.00) | PRKCAPRKCBPRKCEPRKACAPRKACG | |
| SCHEMBL7830883 | 0.83 | PRKCB (0.80) | PRKCAPRKCBPRKCEPIM1JAK2 | |
| SCHEMBL7842048 | 0.82 | PRKCA (0.75) | PRKCAPRKCBPRKCEPRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | claimed |
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |